Title : The development and prevalidation of an in vitro mutagenicity assay based on MutaMouse primary hepatocytes, Part I: Isolation, structural, genetic, and biochemical characterization.

Pub. Date : 2019 May

PMID : 30592088






2 Functional Relationships(s)
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1 Exposure to beta-naphthoflavone led to approximately 900- and 9-fold increases in Cyp1a1 and Cyp1a2 gene expression, respectively, and approximately twofold induction in cytochrome P450 (CYP) 1A1/1A2 activity. beta-Naphthoflavone cytochrome P450 family 1 subfamily A member 1 Homo sapiens
2 Exposure to beta-naphthoflavone led to approximately 900- and 9-fold increases in Cyp1a1 and Cyp1a2 gene expression, respectively, and approximately twofold induction in cytochrome P450 (CYP) 1A1/1A2 activity. beta-Naphthoflavone cytochrome P450 family 1 subfamily A member 1 Homo sapiens