Title : Bisphenol AF exerts estrogenic activity in MCF-7 cells through activation of Erk and PI3K/Akt signals via GPER signaling pathway.

Pub. Date : 2019 Apr

PMID : 30590302






2 Functional Relationships(s)
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Protein Name
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1 BPAF in low concentration significantly enhances the protein expression of estrogen receptor alpha (ERalpha), G protein-coupled receptor (GPER), c-Myc, and Cyclin D1, as well as increases phosphorylation levels of protein kinase B (Akt) and extracellular signal-regulated kinase (Erk) in MCF-7 cells. 4,4'-hexafluorisopropylidene diphenol estrogen receptor 1 Homo sapiens
2 BPAF in low concentration significantly enhances the protein expression of estrogen receptor alpha (ERalpha), G protein-coupled receptor (GPER), c-Myc, and Cyclin D1, as well as increases phosphorylation levels of protein kinase B (Akt) and extracellular signal-regulated kinase (Erk) in MCF-7 cells. 4,4'-hexafluorisopropylidene diphenol estrogen receptor 1 Homo sapiens