Title : Intra-periaqueductal gray matter administration of orexin-A exaggerates pulpitis-induced anxiogenic responses and c-fos expression mainly through the interaction with orexin 1 and cannabinoid 1 receptors in rats.

Pub. Date : 2019 Feb

PMID : 30587409






2 Functional Relationships(s)
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1 Intradental capsaicin induced a significant increase in c-fos expression in the vlPAG that was exaggerated by orexin-A (0.51 mug/rat). Capsaicin Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 Blockage of OX1R and CB1 receptors attenuated the effect of orexin-A on c-fos expression in capsaicin-treated rats. Capsaicin Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus