Pub. Date : 2018 Dec 26
PMID : 30585623
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine also increased alpha1nAChR, calpain-1, matrix metalloproteinase-2 (MMP-2), and MMP-9 expression in the aortic tissue. | Nicotine | matrix metallopeptidase 2 | Mus musculus |
| 2 | Nicotine also increased alpha1nAChR, calpain-1, matrix metalloproteinase-2 (MMP-2), and MMP-9 expression in the aortic tissue. | Nicotine | matrix metallopeptidase 2 | Mus musculus |
| 3 | In vitro, nicotine-induced alpha1nAChR, calpain-1, MMP-2, and MMP-9 expression in mouse vascular smooth muscle cells (MOVAS) and macrophages (RAW264.7), and enhanced the migration and proliferation of these cells. | Nicotine | matrix metallopeptidase 2 | Mus musculus |
| 4 | The effect of nicotine on atherogenesis may be mediated by alpha1nAChR-induced activation of the calpain-1/MMP-2/MMP-9 signaling pathway. | Nicotine | matrix metallopeptidase 2 | Mus musculus |