Pub. Date : 2018 Dec 24
PMID : 30584253
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Whole exome sequencing for the identification of CYP3A7 variants associated with tacrolimus concentrations in kidney transplant patients. | Tacrolimus | cytochrome P450 family 3 subfamily A member 7 | Homo sapiens |
| 2 | The combined set LMM showed that only CYP3A7 rs2257401 was associated with tacrolimus C0/D after adjusting for patient age, albumin, and creatinine. | Tacrolimus | cytochrome P450 family 3 subfamily A member 7 | Homo sapiens |
| 3 | The CYP3A7 rs2257401 genotype variant showed a significant difference on the tacrolimus C0/D in those expressing CYP3A5, showing its own effect. | Tacrolimus | cytochrome P450 family 3 subfamily A member 7 | Homo sapiens |
| 4 | The results suggest that CYP3A7 rs2257401 may serve as a significant genetic marker for tacrolimus pharmacokinetics in kidney transplantation. | Tacrolimus | cytochrome P450 family 3 subfamily A member 7 | Homo sapiens |