Title : Preventive effect of D-carvone during DMBA induced mouse skin tumorigenesis by modulating xenobiotic metabolism and induction of apoptotic events.

Pub. Date : 2019 Mar

PMID : 30583225






1 Functional Relationships(s)
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1 Our results also showed decreased levels of phase I enzymes (Cyt P450 and-Cyt b5) with increased levels of phase II enzymes (GR, GST and GSH) and increased expression of Bax, caspase-3 and caspase-9 with decreased expression of mutated p53 and Bcl-2 in animals treated with DMBA and D-carvone at 20 mg dose. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene BCL2-associated X protein Mus musculus