Title : SUMOylation by SUMO2 is implicated in the degradation of misfolded ataxin-7 via RNF4 in SCA7 models.

Pub. Date : 2019 Jan 11

PMID : 30559154






2 Functional Relationships(s)
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1 In a SCA7 knock-in mouse model, we similarly observed colocalization of SUMO2/3 with polyQ-ATXN7 inclusions in the cerebellum and retina. polyglutamine ataxin 7 Mus musculus
2 In a SCA7 knock-in mouse model, we similarly observed colocalization of SUMO2/3 with polyQ-ATXN7 inclusions in the cerebellum and retina. polyglutamine ataxin 7 Mus musculus