Title : PPARα suppresses Th17 cell differentiation through IL-6/STAT3/RORγt pathway in experimental autoimmune myocarditis.

Pub. Date : 2019 Feb 1

PMID : 30557558






1 Functional Relationships(s)
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1 On the other hand, in isolated CD4+ T cells from experimental autoimmune myocarditis (EAM) rats, PPARalpha agonist Fenofibrate decreased the expression of IL-17 and RORgammat, increased the expression of Foxp3, while PPARalpha antagonist MK886 reversed these effects. MK-886 peroxisome proliferator activated receptor alpha Rattus norvegicus