Title : Pathophysiology of NSAID-Associated Intestinal Lesions in the Rat: Luminal Bacteria and Mucosal Inflammation as Targets for Prevention.

Pub. Date : 2018

PMID : 30555323






1 Functional Relationships(s)
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1 In LPS-primed THP-1 cells stimulated by nigericin (a model to study the NLRP3 inflammasome), rifaximin reduced IL-1beta production in a concentration-dependent fashion, this effect being associated with inhibition of the up-stream caspase-1 activation. Nigericin interleukin 1 beta Homo sapiens