Pub. Date : 2019 Jan 22
PMID : 30554658
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Decreased PKG transcription mediated by PI3K/Akt/FoxO1 pathway is involved in the development of nitroglycerin tolerance. | Nitroglycerin | thymoma viral proto-oncogene 1 | Mus musculus |
2 | The present study is to determine whether PI3K/Akt pathway in vascular smooth muscle cells is involved in nitroglycerin (NTG) tolerance and the underlying mechanism. | Nitroglycerin | thymoma viral proto-oncogene 1 | Mus musculus |
3 | The present study is to determine whether PI3K/Akt pathway in vascular smooth muscle cells is involved in nitroglycerin (NTG) tolerance and the underlying mechanism. | Nitroglycerin | thymoma viral proto-oncogene 1 | Mus musculus |
4 | In conclusion, the present study suggests that PI3K/Akt in vascular smooth muscle is involved in the development of NTG tolerance via inhibiting PKG transcription and the effect is mediated by FoxO1. | Nitroglycerin | thymoma viral proto-oncogene 1 | Mus musculus |