Title : P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) limit brain accumulation of the FLT3 inhibitor quizartinib in mice.

Pub. Date : 2019 Feb 10

PMID : 30553002






2 Functional Relationships(s)
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1 P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) limit brain accumulation of the FLT3 inhibitor quizartinib in mice. quizartinib FMS-like tyrosine kinase 3 Mus musculus
2 Quizartinib, a second-generation FLT3 inhibitor, is in clinical development for the treatment of acute myeloid leukemia. quizartinib FMS-like tyrosine kinase 3 Mus musculus