Pub. Date : 2019 Mar 15
PMID : 30552925
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Eukaryotic Initiation Factor 4E (eIF4E) sequestration mediates 4E-BP1 response to rapamycin. | Sirolimus | eukaryotic translation initiation factor 4E | Homo sapiens |
| 2 | Eukaryotic Initiation Factor 4E (eIF4E) sequestration mediates 4E-BP1 response to rapamycin. | Sirolimus | eukaryotic translation initiation factor 4E | Homo sapiens |
| 3 | The data presented in this study identifies eIF4E and not Raptor as a cellular factor responsible to regulate rapamycin sensitivity of 4E-BP1 suggesting that the phosphorylation dynamics and rapamycin sensitivity of 4E-BP1 and S6K1 are regulated independently. | Sirolimus | eukaryotic translation initiation factor 4E | Homo sapiens |