Title : A new pyrrole based small molecule from Tinospora cordifolia induces apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity.

Pub. Date : 2019 Feb 1

PMID : 30543781






1 Functional Relationships(s)
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1 TCCP treatment caused endogenous ROS generation, increase in intracellular calcium and phosphorylation of p53 in a concentration-dependent manner, which was reverted upon pre-treatment with pifithrin-mu. pifithrin tumor protein p53 Homo sapiens