Title : The Significance of BRAFV600E Mutation in Thyroid Cancer in Terms of Novel Targeted Therapies - Overview of Current Knowledge and Studies.

Pub. Date : Fall 2018

PMID : 30541319






1 Functional Relationships(s)
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1 AIM: The aim of this review is to discuss the significance of the BRAF mutation mostly in radioiodine-refractory thyroid cancers (RR-TC) with respect to recent preclinical and clinical studies reporting the results of different RAF and MEK inhibitors. Iodine-131 B-Raf proto-oncogene, serine/threonine kinase Homo sapiens