Pub. Date : 2019 Mar 1
PMID : 30541118
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Improvement in insulin sensitivity and serum leptin concentration after the switch from a ritonavir-boosted PI to raltegravir or dolutegravir in non-diabetic HIV-infected patients. | dolutegravir | insulin | Homo sapiens |
2 | CONCLUSIONS: In HIV-positive subjects on suppressive cART, the switch from a PI/r to raltegravir or dolutegravir led to a significant and comparable reduction in both HOMA index and serum leptin level, reflecting a similar and significant improvement in insulin sensitivity. | dolutegravir | insulin | Homo sapiens |