Title : SIRT1 knockdown up-regulates p53 and p21/Cip1 expression in renal adenocarcinoma cells but not in normal renal-derived cells in a deacetylase-independent manner.

Pub. Date : 2018

PMID : 30518708






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 SIRT1, an NAD+-dependent deacetylase, causes deacetylation and down-regulation of its target p53. NAD tumor protein p53 Homo sapiens