Title : Nuclear magnetic resonance metabolic fingerprint of bevacizumab in mutant IDH1 glioma cells.

Pub. Date : 2018 Nov 26

PMID : 30511933






1 Functional Relationships(s)
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1 These data support the possibility of a functional tricarboxylic acid cycle that runs in reductive manner, as a probable mechanism of action of bevacizumab in IDH1 mutated gliomas and propose a new target pathway for effective treatment of malignant gliomas. Tricarboxylic Acids isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens