Title : Cooperative assembly of a four-molecule signaling complex formed upon T cell antigen receptor activation.

Pub. Date : 2018 Dec 18

PMID : 30510001






1 Functional Relationships(s)
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1 One such enzyme, phospholipase-Cgamma1, is responsible for cleavage of a plasma membrane lipid substrate, a phosphoinositide, into two second messengers, diacylglycerol, which activates several enzymes including protein kinase C, and an inositol phosphate, which induces intracellular calcium elevation. Phosphatidylinositols phospholipase C gamma 1 Homo sapiens