Title : Folate deficiency drives mitotic missegregation of the human FRAXA locus.

Pub. Date : 2018 Dec 18

PMID : 30509972






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Many RFSs, as exemplified by expansion of a CGG trinucleotide repeat sequence in the fragile X syndrome-associated FRAXA locus, exhibit fragility in response to folate deficiency or other forms of "folate stress." Folic Acid fragile site, folic acid type, rare, fra(X)(q27.3) A (macroorchidism, mental retardation) Homo sapiens