Pub. Date : 2019 Feb
PMID : 30508725
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment with the synthetic PPARG ligand pioglitazone ameliorates early ovarian alterations induced by dehydroepiandrosterone in prepubertal rats. | Pioglitazone | peroxisome proliferator-activated receptor gamma | Rattus norvegicus |
| 2 | The aim of the present study was to evaluate whether PPARG activation (using the synthetic ligand pioglitazone (PGZ)) ameliorates the alterations in early ovarian function induced by androgen excess. | Pioglitazone | peroxisome proliferator-activated receptor gamma | Rattus norvegicus |
| 3 | The aim of the present study was to evaluate whether PPARG activation (using the synthetic ligand pioglitazone (PGZ)) ameliorates the alterations in early ovarian function induced by androgen excess. | Pioglitazone | peroxisome proliferator-activated receptor gamma | Rattus norvegicus |
| 4 | RESULTS: PGZ prevented the inactivation of ovarian PPARG induced by androgen excess by increasing PPARG itself and the gene expression of PPARG-coactivator 1 alpha (PGC1A), and by decreasing the gene expression of nuclear co-repressor (NCOR). | Pioglitazone | peroxisome proliferator-activated receptor gamma | Rattus norvegicus |
| 5 | RESULTS: PGZ prevented the inactivation of ovarian PPARG induced by androgen excess by increasing PPARG itself and the gene expression of PPARG-coactivator 1 alpha (PGC1A), and by decreasing the gene expression of nuclear co-repressor (NCOR). | Pioglitazone | peroxisome proliferator-activated receptor gamma | Rattus norvegicus |