Title : Targeting the arginine metabolic brake enhances immunotherapy for leukaemia.

Pub. Date : 2019 Oct 15

PMID : 30485425






2 Functional Relationships(s)
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1 Examination of AML patients treated with azacitidine (AZA) and vorinostat (VOR) in a Phase II trial, demonstrated an increase in the expression of Cancer-Testis Antigens (MAGE, RAGE, LAGE, SSX2 and TRAG3) on blasts and that these can be recognised by circulating antigen-specific T cells. Azacitidine long intergenic non-protein coding RNA 914 Homo sapiens
2 Examination of AML patients treated with azacitidine (AZA) and vorinostat (VOR) in a Phase II trial, demonstrated an increase in the expression of Cancer-Testis Antigens (MAGE, RAGE, LAGE, SSX2 and TRAG3) on blasts and that these can be recognised by circulating antigen-specific T cells. Azacitidine long intergenic non-protein coding RNA 914 Homo sapiens