Pub. Date : 2019 Feb
PMID : 30483812
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Levistolide A synergistically enhances doxorubicin-induced apoptosis of k562/dox cells by decreasing MDR1 expression through the ubiquitin pathway. | Doxorubicin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Furthermore, multidrug resistance protein 1 (MDR1) expression in k562/dox cells was downregulated by levistolide A in a dose-dependent manner, thus suggesting that levistolide A may modulate MDR1 during cancer therapy. | Doxorubicin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | Furthermore, multidrug resistance protein 1 (MDR1) expression in k562/dox cells was downregulated by levistolide A in a dose-dependent manner, thus suggesting that levistolide A may modulate MDR1 during cancer therapy. | Doxorubicin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | Furthermore, multidrug resistance protein 1 (MDR1) expression in k562/dox cells was downregulated by levistolide A in a dose-dependent manner, thus suggesting that levistolide A may modulate MDR1 during cancer therapy. | Doxorubicin | ATP binding cassette subfamily B member 1 | Homo sapiens |