Title : Isorhamnetin alleviates lipopolysaccharide-induced inflammatory responses in BV2 microglia by inactivating NF-κB, blocking the TLR4 pathway and reducing ROS generation.

Pub. Date : 2019 Feb

PMID : 30483725






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The mechanism underlying the anti-inflammatory effects of isorhamnetin was subsequently evaluated; this flavonoid inhibited the nuclear factor (NF)-kappaB signaling pathway by disrupting degradation and phosphorylation of inhibitor kappaB-alpha in the cytoplasm and blocking translocation of NF-kappaB p65 into the nucleus. 3-methylquercetin v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus