Title : Aspirin ameliorates experimental autoimmune encephalomyelitis through interleukin-11-mediated protection of regulatory T cells.

Pub. Date : 2018 Nov 27

PMID : 30482850






1 Functional Relationships(s)
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1 Aspirin also increased the transcription of Il11 mediated by the transcription factor CREB, which was necessary for the generation of Tregs Neutralization of IL-11 negated the effects of aspirin on Treg development and exacerbated EAE. treg cAMP responsive element binding protein 1 Mus musculus