Title : Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry.

Pub. Date : 2019 Jan

PMID : 30472464






2 Functional Relationships(s)
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1 Further, the smoking cessation agents, nicotine, varenicline and cytisine increased activation of mutant (alpha4)3(beta2)2 receptors, while only nicotine increased activation of mutant (alpha4)2(beta2)3 receptors. Nicotine potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens
2 Further, the smoking cessation agents, nicotine, varenicline and cytisine increased activation of mutant (alpha4)3(beta2)2 receptors, while only nicotine increased activation of mutant (alpha4)2(beta2)3 receptors. Nicotine potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens