Pub. Date : 2019 Jan
PMID : 30472461
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Recent evidence indicates that alcohol exposure increased the activity of MCP-1/CCR2 in both mature and developing central nervous systems (CNS). | Alcohols | C-C motif chemokine ligand 2 | Homo sapiens |
2 | MCP-1/CCR2 signaling in the brain was involved in alcohol drinking behavior. | Alcohols | C-C motif chemokine ligand 2 | Homo sapiens |
3 | MCP-1/CCR2 inhibition alleviated alcohol neurotoxicity by reducing microglia activation/neuroinflammation in the developing brain and spinal cord. | Alcohols | C-C motif chemokine ligand 2 | Homo sapiens |
4 | In this review, we discussed the role of MCP-1/CCR2 signaling in alcohol-induced neuroinflammation and brain damage. | Alcohols | C-C motif chemokine ligand 2 | Homo sapiens |
5 | We also discussed the signaling cascades that are involved in the activation of MCP-1/CCR2 in response to alcohol exposure. | Alcohols | C-C motif chemokine ligand 2 | Homo sapiens |