Title : Structural Insights of Stereospecific Inhibition of Human Acetylcholinesterase by VX and Subsequent Reactivation by HI-6.

Pub. Date : 2018 Dec 17

PMID : 30462502






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Structural Insights of Stereospecific Inhibition of Human Acetylcholinesterase by VX and Subsequent Reactivation by HI-6. asoxime chloride acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Beyond identifying hAChE structural features that lend themselves to stereospecific inhibition, structures of the reactivator HI-6 bound to hAChE inhibited by VX enantiomers of varying toxicity, or in its uninhibited state, were obtained. asoxime chloride acetylcholinesterase (Cartwright blood group) Homo sapiens