Title : Suppression of ovarian follicle development by nano TiO2 is associated with TGF-β-mediated signaling pathways.

Pub. Date : 2019 Feb

PMID : 30461191






1 Functional Relationships(s)
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1 Furthermore, follicular development disorder induced by nano TiO2 was associated with upregulation of TGF-beta1, TGF-betaR1, PTEN, and Foxo3a involved in cell growth and apoptosis and downregulation of several growth factors (PI3K, AKT, p-mTOR, p70S6K, p-p70S6K1, rpS6, p-rpS6, TSC1, and TSC2) in mouse ovaries. titanium dioxide TSC complex subunit 2 Mus musculus