Pub. Date : 2018
PMID : 30450337
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recent studies have found that p53 acts as a positive regulator of ferroptosis by promoting ROS production. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 2 | p53 directly regulates the metabolic versatility of cells by favoring mitochondrial respiration, leading to ROS-mediated ferroptosis. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 3 | In mild stress, p53 protects cell survival via eliminating ROS; additionally, in human colorectal cancer, p53 antagonizes ferroptosis by formation of the DPP4-p53 complex. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 4 | In mild stress, p53 protects cell survival via eliminating ROS; additionally, in human colorectal cancer, p53 antagonizes ferroptosis by formation of the DPP4-p53 complex. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 5 | In mild stress, p53 protects cell survival via eliminating ROS; additionally, in human colorectal cancer, p53 antagonizes ferroptosis by formation of the DPP4-p53 complex. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 6 | In short, the mechanisms of p53-mediated ROS production underlying cellular response are poorly understood. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 7 | In the context of recent research results, the indistinct roles of p53 on ROS-mediated ferroptosis are scrutinized to understand the mechanism underlying p53-mediated tumor suppression. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 8 | In the context of recent research results, the indistinct roles of p53 on ROS-mediated ferroptosis are scrutinized to understand the mechanism underlying p53-mediated tumor suppression. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |