Title : Butyrate Modulates Inflammation in Chondrocytes via GPR43 Receptor.

Pub. Date : 2018

PMID : 30448827






1 Functional Relationships(s)
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1 RESULTS: Butyrate reduced the expression of canonic pro-inflammatory mediators (Nos2, COX-2, IL-6), pro-inflammatory adipokines (lipocalin-2 and nesfatin-1) and adhesion molecule (VCAM-1 and ICAM-1) in IL-1beta-stimulated chondrocytes, inhibiting several inflammatory signalling pathways (NFkappaB, MAPKinase, AMPK-alpha, PI3K/Akt). Butyrates nitric oxide synthase 2, inducible Mus musculus