Title : Characterization of kinetics of human cytochrome P450s involved in bioactivation of flucloxacillin: inhibition of CYP3A-catalysed hydroxylation by sulfaphenazole.

Pub. Date : 2019 Feb

PMID : 30447161






1 Functional Relationships(s)
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1 CONCLUSIONS AND IMPLICATIONS: The combined results show that the 5"-hydroxylation of flucloxacillin is primarily catalysed by CYP3A4, CYP3A7 and CYP2C9. Floxacillin cytochrome P450 family 2 subfamily C member 9 Homo sapiens