Title : Metformin suppresses the esophageal carcinogenesis in rats treated with NMBzA through inhibiting AMPK/mTOR signaling pathway.

Pub. Date : 2019 Jul 4

PMID : 30445633






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1 Taken together, our study demonstrated that metformin suppressed the carcinogenesis of ESCC through inhibiting AMPK/mammalian target of the rapamycin (mTOR) signaling pathway, resulting in its chemopreventive effects on the carcinogenesis of ESCC. Sirolimus protein kinase AMP-activated non-catalytic subunit beta 1 Homo sapiens