Pub. Date : 2019 Feb
PMID : 30443761
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Knockdown of long non-coding HOTAIR enhances the sensitivity to progesterone in endometrial cancer by epigenetic regulation of progesterone receptor isoform B. | Progesterone | HOX transcript antisense RNA | Homo sapiens |
| 2 | In this study, we aim to investigate the effect of long non-coding RNA HOTAIR on progesterone sensitivity in endometrial cancer, as well as the underlying mechanisms. | Progesterone | HOX transcript antisense RNA | Homo sapiens |
| 3 | CONCLUSIONS: Our findings provide compelling evidence that HOTAIR and LSD1 collaboratively repress PRB expression and thus mediate progesterone sensitivity in endometrial carcinoma cells. | Progesterone | HOX transcript antisense RNA | Homo sapiens |
| 4 | HOTAIR is a potential predictor for progesterone response in EC and down-regulated expression of HOTAIR might be an effective strategy for overcoming progesterone resistance. | Progesterone | HOX transcript antisense RNA | Homo sapiens |