Title : [Relationship between UGT1A4 142T>G polymorphism and serum concentration of lamotrigine in Chinese epileptic patients: a meta-analysis].

Pub. Date : 2018 Nov 6

PMID : 30440130






1 Functional Relationships(s)
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1 Conclusion: UGT1A4 142T>G polymorphism has an effect on LTG concentration only with VPA co-administration in Chinese epileptic pediatric patients and those children with wild-type (TT genotype) have a tendency to have a lower serum concentration of lamotrigine. Valproic Acid UDP glucuronosyltransferase family 1 member A4 Homo sapiens