Title : EGFR mutation decreases FDG uptake in non‑small cell lung cancer via the NOX4/ROS/GLUT1 axis.

Pub. Date : 2019 Jan

PMID : 30431083






2 Functional Relationships(s)
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1 EGFR mutation decreases FDG uptake in non-small cell lung cancer via the NOX4/ROS/GLUT1 axis. Reactive Oxygen Species solute carrier family 2 member 1 Homo sapiens
2 Reverse transcription-polymerase chain reaction indicated that the GLUT1 mRNA decreased in the PC-9 and NCI-H1975 cell lines compared with the A549 cell line (0.82+-0.07 and 0.72+-0.04 vs. 0.98+-0.04, respectively; P<0.05) and decreased ROS activity was observed in the PC-9 cell line. Reactive Oxygen Species solute carrier family 2 member 1 Homo sapiens