Pub. Date : 2019 Jan 1
PMID : 30423122
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, we found that testosterone induced expression of various UPR genes, including CHOP, as well as DR5, in cultured human granulosa-lutein cells (GLCs). | Testosterone | DNA damage inducible transcript 3 | Homo sapiens |
| 2 | Pretreatment with the ER stress inhibitor tauroursodeoxycholic acid (TUDCA) inhibited testosterone-induced apoptosis and expression of DR5 and CHOP. | Testosterone | DNA damage inducible transcript 3 | Homo sapiens |
| 3 | Knockdown of CHOP inhibited testosterone-induced DR5 expression and apoptosis, and knockdown of DR5 inhibited testosterone-induced apoptosis. | Testosterone | DNA damage inducible transcript 3 | Homo sapiens |
| 4 | Pretreatment with flutamide, as well as knockdown of androgen receptor, decreased testosterone-induced DR5 and CHOP expression, as well as apoptosis. | Testosterone | DNA damage inducible transcript 3 | Homo sapiens |