Title : Identification of 19-(S/R)Hydroxyeicosatetraenoic Acid as the First Endogenous Noncompetitive Inhibitor of Cytochrome P450 1B1 with Enantioselective Activity.

Pub. Date : 2019 Feb

PMID : 30420405






1 Functional Relationships(s)
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1 In the current study, we report that 19(S/R)-HETE enantioselectively inhibits human recombinant CYP1B1 activity measured by 7-ethoxyresorufin O-deethylation assay. ethoxyresorufin cytochrome P450 family 1 subfamily B member 1 Homo sapiens