Title : α-Mangostin exhibits antidepressant-like effects mediated by the modification of GABAergic, serotonergic and dopaminergic systems.

Pub. Date : 2020 Mar

PMID : 30417675






1 Functional Relationships(s)
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1 exhibited markedly antidepressant-like activity, which could be reversed by pretreatment with haloperidol (a non-selective D2 receptor antagonist), bicuculline (a competitive GABA antagonist), p-chlorophenylalanine (an inhibitor of 5-HT synthesis). Haloperidol dopamine receptor D2 Mus musculus