Title : Neostigmine Attenuates Proinflammatory Cytokine Expression in Preoptic Area but Not Choroid Plexus during Lipopolysaccharide-Induced Systemic Inflammation.

Pub. Date : 2018

PMID : 30402044






1 Functional Relationships(s)
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1 Neostigmine suppressed (p < 0.05) LPS-stimulated synthesis of cytokines such as interleukin- (IL-) 1beta, IL-6, and tumor necrosis factor (TNF) alpha in the POA, and this effect was similar to that induced by the treatment with systemic AChE inhibitor-donepezil (2.5 mg/animal). lps acetylcholinesterase (Cartwright blood group) Homo sapiens