Title : Anticancer effect of pan-PI3K inhibitor on multiple myeloma cells: Shedding new light on the mechanisms involved in BKM120 resistance.

Pub. Date : 2019 Jan 5

PMID : 30401630






1 Functional Relationships(s)
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1 As far as we are aware, the results of the present study propose for the first time that the inhibitory effect of BKM120 was overshadowed, at least partially, through over-expression of either c-Myc or nuclear factor (NF)-kappaB in less sensitive MM cells. NVP-BKM120 nuclear factor kappa B subunit 1 Homo sapiens