Title : Immuno-oncology agent IPI-549 is a modulator of P-glycoprotein (P-gp, MDR1, ABCB1)-mediated multidrug resistance (MDR) in cancer: In vitro and in vivo.

Pub. Date : 2019 Feb 1

PMID : 30391357






2 Functional Relationships(s)
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Protein Name
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1 The combination of IPI-549 with paclitaxel showed that IPI-549 potentiates the anti-tumor effects of paclitaxel in P-gp-overexpressing MDR SW620/Ad300 xenograft tumors. Paclitaxel ATP binding cassette subfamily B member 1 Homo sapiens
2 The combination of IPI-549 with paclitaxel showed that IPI-549 potentiates the anti-tumor effects of paclitaxel in P-gp-overexpressing MDR SW620/Ad300 xenograft tumors. Paclitaxel ATP binding cassette subfamily B member 1 Homo sapiens