Title : Synthesis and biological evaluation of quinazoline derivatives - A SAR study of novel inhibitors of ABCG2.

Pub. Date : 2019 Jan 1

PMID : 30390439






1 Functional Relationships(s)
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1 MDR is often associated with the overexpression of ABC transport proteins like ABCB1 or ABCG2 which efflux harmful substances out of cells at the cost of ATP hydrolysis. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens