Title : Copper Redox Cycling Inhibits Aβ Fibre Formation and Promotes Fibre Fragmentation, while Generating a Dityrosine Aβ Dimer.

Pub. Date : 2018 Nov 1

PMID : 30385800






1 Functional Relationships(s)
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1 Using fluorescence measurements and UV absorbance, we show that dityrosine can be formed aerobically when Abeta is incubated with Cu2+ and hydrogen-peroxide, or in a Cu2+ and ascorbate redox mixture. Hydrogen Peroxide amyloid beta precursor protein Homo sapiens