Title : [Elucidation of a New Mechanism of Onset of Insulin Resistance: Effects of Statins and Tumor Necrosis Factor-α on Insulin Signal Transduction].

Pub. Date : 2018

PMID : 30381640






1 Functional Relationships(s)
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1 Interestingly, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, an AMP-activated protein kinase activator, suppresses TNF-alpha-induced IRS-1 serine phosphorylation at 636/639 and the phosphorylation of ERK by enhancing interactions between ERK and dual-specificity phosphatase-9. acadesine dual specificity phosphatase 9 Homo sapiens