Title : Pioglitazone Reduces Hepatocellular Carcinoma Development in Two Rodent Models of Cirrhosis.

Pub. Date : 2019 Jan

PMID : 30367397






1 Functional Relationships(s)
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1 In both models, pioglitazone reduced the activation of mitogen-activated protein kinase (MAPK) and upregulated the hepato-protective AMP-activated protein kinase (AMPK) pathway via increasing circulating adiponectin production. Pioglitazone adiponectin, C1Q and collagen domain containing Rattus norvegicus