Title : S1P1 receptor phosphorylation, internalization, and interaction with Rab proteins: effects of sphingosine 1-phosphate, FTY720-P, phorbol esters, and paroxetine.

Pub. Date : 2018 Dec 21

PMID : 30366961






1 Functional Relationships(s)
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1 The ability of bisindolylmaleimide I and paroxetine to block some of these actions suggested the activation of protein kinase C was associated mainly with the action of PMA, whereas G protein-coupled receptor kinase (GRK) 2 (GRK2) was involved in the action of the three agents. Paroxetine G protein-coupled receptor kinase 2 Homo sapiens