Title : The Serum Level of IL-1B Correlates with the Activity of Chronic Pulmonary Aspergillosis.

Pub. Date : 2018

PMID : 30363691






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1 This study aims to analyze the correlation between serum level of IL-1B and the activity of CPA and to determine whether serum IL-1B could be used to assess the activity of CPA. cpa interleukin 1 beta Homo sapiens
2 This study aims to analyze the correlation between serum level of IL-1B and the activity of CPA and to determine whether serum IL-1B could be used to assess the activity of CPA. cpa interleukin 1 beta Homo sapiens
3 Correlation analysis in the whole subjects showed that only IL-1B level was associated with the activity of CPA. cpa interleukin 1 beta Homo sapiens
4 In subgroup comparative analysis, CT characteristics suggested that high activity of CPA, such as cavitary (27/44 vs 13/44, P=0.003) and aspergilloma lesions (25/44 vs. 11/44, P<0.002), were more frequently found in high IL-1B group. cpa interleukin 1 beta Homo sapiens
5 Interestingly, a significant reduction of IL-1B level was observed after successful resection of CPA lesions. cpa interleukin 1 beta Homo sapiens
6 Conclusion: Higher level of serum IL-1B is associated with more severe cavitary and aspergilloma lesions, which are indicative of more active CPA. cpa interleukin 1 beta Homo sapiens
7 Measuring IL-1B level therefore could be served as a convenient method to monitor the activity of CPA and be a potential predictive/prognostic marker for treatment response. cpa interleukin 1 beta Homo sapiens