Title : Red wine and green tea flavonoids are cis-allosteric activators and competitive inhibitors of glucose transporter 1 (GLUT1)-mediated sugar uptake.

Pub. Date : 2018 Dec 21

PMID : 30361436






3 Functional Relationships(s)
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1 Red wine and green tea flavonoids are cis-allosteric activators and competitive inhibitors of glucose transporter 1 (GLUT1)-mediated sugar uptake. Sugars solute carrier family 2 member 1 Homo sapiens
2 Red wine and green tea flavonoids are cis-allosteric activators and competitive inhibitors of glucose transporter 1 (GLUT1)-mediated sugar uptake. Sugars solute carrier family 2 member 1 Homo sapiens
3 Docking studies suggest that only one flavonoid can bind to GLUT1 at any instant, but sugar transport and ligand-binding studies indicate that human erythrocyte GLUT1 can bind at least two flavonoid molecules simultaneously. Sugars solute carrier family 2 member 1 Homo sapiens