Title : PARP inhibitors affect growth, survival and radiation susceptibility of human alveolar and embryonal rhabdomyosarcoma cell lines.

Pub. Date : 2019 Jan

PMID : 30357520






1 Functional Relationships(s)
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1 Downregulation of phospho-AKT levels and accumulation of gammaH2AX, a specific marker of DNA damage, were significantly and persistently induced by Olaparib and AZD2461 exposure, this leading to apoptosis-related cell death. olaparib AKT serine/threonine kinase 1 Homo sapiens