Pub. Date : 2018 Jan-Dec
PMID : 30354842
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Taurine attenuates acrylamide-induced axonal and myelinated damage through the Akt/GSK3beta-dependent pathway. | Taurine | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 2 | Furthermore, the GSK3beta phosphorylation in taurine-treated dorsal root ganglion (DRG) with ACR was examined in the presence of the Akt inhibitor, MK-2206. | Taurine | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 3 | The analysis of behavioral performances and electron micrographs indicated that taurine treatment significantly attenuated the toxic manifestations induced by ACR and stimulated the growth of axons and the medullary sheath, which was associated with the activation of the Akt/GSK3beta signaling pathway. | Taurine | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 4 | Furthermore, MK-2206, an inhibitor of Akt, was applied in DRG cells, suggesting that taurine-induced GSK3beta phosphorylation was Akt dependent. | Taurine | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 5 | Furthermore, MK-2206, an inhibitor of Akt, was applied in DRG cells, suggesting that taurine-induced GSK3beta phosphorylation was Akt dependent. | Taurine | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 6 | Our findings demonstrated that taurine attenuated ACR-induced neuropathy in vivo, in an Akt/GSK3beta-dependent manner. | Taurine | AKT serine/threonine kinase 1 | Rattus norvegicus |